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CADASIL RESEARCH:
IMAGING

Imaging
Cumurci
uc R, Guichard JP, Reizine D, Gray F, Bousser MG, Chabriat H. Dilation of Virchow-Robin spaces in CADASIL. Eur J Neurol. 2006;13:187-90.
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O'Sullivan M, Barrick TR, Morris RG, Clark CA, Markus HS. Damage within a network of white matter regions underlies executive dysfunction in CADASIL. Neurology. 2005;65:1584-90.
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Singhal S, Rich P, Markus HS. The spatial distribution of MR imaging abnormalities in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy and their relationship to age and clinical features. AJNR Am J Neuroradiol. 2005;26:2481-7.
Abstract

Holtmannspotter M, Peters N, Opherk C, Martin D, Herzog J, Bruckmann H, Samann P, Gschwendtner A, Dichgans M. Diffusion magnetic resonance histograms as a surrogate marker and predictor of disease progression in CADASIL: a two-year follow-up study. Stroke. 2005;36:2559-65.
Abstract

Peters N, Opherk C, Danek A, Ballard C, Herzog J, Dichgans M. The pattern of cognitive performance in CADASIL: a monogenic condition leading to subcortical ischemic vascular dementia. Am J Psychiatry. 2005;162:2078-85.
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Fattapposta F, Restuccia R, Pirro C, Malandrini A, Locuratolo N, Amabile G, Bianco F. Early diagnosis in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL): the role of MRI. Funct Neurol. 2004 Oct-Dec;19(4):239-42.
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Vahedi K, Chabriat H, Levy C, Joutel A, Tournier-Lasserve E, Bousser MG. Migraine with aura and brain magnetic resonance imaging abnormalities in patients with CADASIL. Arch Neurol. 2004 Aug;61(8):1237-40.
Abstract  

Tuominen S, Miao Q, Kurki T, Tuisku S, Poyhonen M, Kalimo H, Viitanen M, Sipila HT, Bergman J, Rinne JO. Positron emission tomography examination of cerebral blood flow and glucose metabolism in young CADASIL patients. Stroke. 2004 May;35(5):1063-7.
Abstract   Free Full Text Article

O'Sullivan M, Singhal S, Charlton R, Markus HS. Diffusion tensor imaging of thalamus correlates with cognition in CADASIL without dementia. Neurology. 2004 Mar 9;62(5):702-7.
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van den Boom R, Lesnik Oberstein SA, Ferrari MD, Haan J, van Buchem MA. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: MR imaging findings at different ages--3rd-6th decades. Radiology. 2003 Dec;229(3):683-90.
Abstract  Free Full Text Article

O'Sullivan M, Rich PM, Barrick TR, Clark CA, Markus HS. Frequency of subclinical lacunar infarcts in ischemic leukoaraiosis and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. AJNR Am J Neuroradiol. 2003 Aug;24(7):1348-54.
Abstract  Free Full Text Article

Tatsch K, Koch W, Linke R, Poepperl G, Peters N, Holtmannspoetter M, Dichgans M. Cortical hypometabolism and crossed cerebellar diaschisis suggest subcortically induced disconnection in CADASIL: an 18F-FDG PET study. J Nucl Med. 2003 Jun;44(6):862-9.
Abstract

van den Boom R, Lesnik Oberstein SA, Spilt A, Behloul F, Ferrari MD, Haan J, Westendorp RG, van Buchem MA. Cerebral hemodynamics and white matter hyperintensities in CADASIL. J Cereb Blood Flow Metab. 2003 May;23(5):599-604.
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Moon SY, Ki CS, Kim JW, Suh YL, Kwon JC, Na DL. Silent infarcts demonstrated by diffusion-weighted MRI in CADASIL. Eur Neurol. 2003;49(3):178-80.
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Molko N, Pappata S, Mangin JF, Poupon F, LeBihan D, Bousser MG, Chabriat H. Monitoring disease progression in CADASIL with diffusion magnetic resonance imaging: a study with whole brain histogram analysis. Stroke. 2002 Dec;33(12):2902-8.
Abstract   Free Full Text Article

O'Riordan S, Nor AM, Hutchinson M. CADASIL imitating multiple sclerosis: the importance of MRI markers. Mult Scler. 2002 Oct;8(5):430-2.
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van Den Boom R, Lesnik Oberstein SA, van Duinen SG, Bornebroek M, Ferrari MD, Haan J, van Buchem MA. Subcortical lacunar lesions: an MR imaging finding in patients with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Radiology. 2002 Sep;224(3):791-6.
Abstract  Free Full Text Article

Liebetrau M, Herzog J, Kloss CU, Hamann GF, Dichgans M. Prolonged cerebral transit time in CADASIL: a transcranial ultrasound study. Stroke. 2002 Feb;33(2):509-12.
Abstract  Free Full Text Article

Reddy H, De Stefano N, Mortilla M, Federico A, Matthews PM. Functional reorganization of motor cortex increases with greater axonal injury from CADASIL. Stroke. 2002 Feb;33(2):502-8.
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Dichgans M, Holtmannspotter M, Herzog J, Peters N, Bergmann M, Yousry TA. Cerebral microbleeds in CADASIL: a gradient-echo magnetic resonance imaging and autopsy study. Stroke. 2002 Jan;33(1):67-71.
Abstract  Free Full Text Article

Molko N, Pappata S, Mangin JF, Poupon C, Vahedi K, Jobert A, LeBihan D, Bousser MG, Chabriat H. Diffusion tensor imaging study of subcortical gray matter in cadasil. Stroke. 2001 Sep;32(9):2049-54.
Abstract  Free Full Text Article

Bruening R, Dichgans M, Berchtenbreiter C, Yousry T, Seelos KC, Wu RH, Mayer M, Brix G, Reiser M. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy: decrease in regional cerebral blood volume in hyperintense subcortical lesions inversely correlates with disability and cognitive performance. AJNR Am J Neuroradiol. 2001 Aug;22(7):1268-74.
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Rocca MA, Filippi M, Herzog J, Sormani MP, Dichgans M, Yousry TA. A magnetic resonance imaging study of the cervical cord of patients with CADASIL. Neurology. 2001 May 22;56(10):1392-4.
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Auer DP, Schirmer T, Heidenreich JO, Herzog J, Putz B, Dichgans M. Altered white and gray matter metabolism in CADASIL: a proton MR spectroscopy and 1H-MRSI study. Neurology. 2001 Mar 13;56(5):635-42.
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O'Sullivan M, Jarosz JM, Martin RJ, Deasy N, Powell JF, Markus HS. MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL. Neurology. 2001 Mar 13;56(5):628-34.
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Iannucci G, Dichgans M, Rovaris M, Bruning R, Gasser T, Giacomotti L, Yousry TA, Filippi M. Correlations between clinical findings and magnetization transfer imaging metrics of tissue damage in individuals with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy. Stroke. 2001 Mar;32(3):643-8.
Abstract   Free Full Text Article

Auer DP, Putz B, Gossl C, Elbel G, Gasser T, Dichgans M. Differential lesion patterns in CADASIL and sporadic subcortical arteriosclerotic encephalopathy: MR imaging study with statistical parametric group comparison. Radiology. 2001 Feb;218(2):443-51.
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Pfefferkorn T, von Stuckrad-Barre S, Herzog J, Gasser T, Hamann GF, Dichgans M. Reduced cerebrovascular CO(2) reactivity in CADASIL: A transcranial Doppler sonography study. Stroke. 2001 Jan;32(1):17-21.
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Chabriat H, Pappata S, Ostergaard L, Clark CA, Pachot-Clouard M, Vahedi K, Jobert A, Le Bihan D, Bousser MG. Cerebral hemodynamics in CADASIL before and after acetazolamide challenge assessed with MRI bolus tracking. Stroke. 2000 Aug;31(8):1904-12.
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Chawda SJ, De Lange RP, Hourihan MD, Halpin SF, St Clair D. Diagnosing CADASIL using MRI: evidence from families with known mutations of Notch 3 gene. Neuroradiology. 2000 Apr;42(4):249-55.
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Coulthard A, Blank SC, Bushby K, Kalaria RN, Burn DJ. Distribution of cranial MRI abnormalities in patients with symptomatic and subclinical CADASIL. Br J Radiol. 2000 Mar;73(867):256-65.
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Chabriat H, Pappata S, Poupon C, Clark CA, Vahedi K, Poupon F, Mangin JF, Pachot-Clouard M, Jobert A, Le Bihan D, Bousser MG. Clinical severity in CADASIL related to ultrastructural damage in white matter: in vivo study with diffusion tensor MRI. Stroke. 1999 Dec;30(12):2637-43.
Abstract   Free Full Text Article

Dichgans M, Filippi M, Bruning R, Iannucci G, Berchtenbreiter C, Minicucci L, Uttner I, Crispin A, Ludwig H, Gasser T, Yousry TA. Quantitative MRI in CADASIL: correlation with disability and cognitive performance. Neurology. 1999 Apr 22;52(7):1361-7.
Abstract

Yousry TA, Seelos K, Mayer M, Bruning R, Uttner I, Dichgans M, Mammi S, Straube A, Mai N, Filippi M. Characteristic MR lesion pattern and correlation of T1 and T2 lesion volume with neurologic and neuropsychological findings in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). AJNR Am J Neuroradiol. 1999 Jan;20(1):91-100.
Abstract   Free Full Text Article

Chabriat H, Mrissa R, Levy C, Vahedi K, Taillia H, Iba-Zizen MT, Joutel A, Tournier-Lasserve E, Bousser MG. Brain stem MRI signal abnormalities in CADASIL. Stroke. 1999 Feb;30(2):457-9.
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Chabriat H, Levy C, Taillia H, Iba-Zizen MT, Vahedi K, Joutel A, Tournier-Lasserve E, Bousser MG. Patterns of MRI lesions in CADASIL. Neurology. 1998 Aug;51(2):452-7.
Abstract

Mellies JK, Baumer T, Muller JA, Tournier-Lasserve E, Chabriat H, Knobloch O, Hackeloer HJ, Goebel HH, Wetzig L, Haller P. SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only. Neurology. 1998 Jun;50(6):1715-21.
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