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About Depression - Mood Disorders

Back to Mood Disorders Research Program main page

Statistics

  • Mood disorders are serious illnesses that affect 15-20% of all Americans at some time in their lives.
  • Depression is currently the leading cause of disability in developed countries, and the fourth leading cause of disability worldwide.
  • Depression's annual toll on U.S. businesses amounts to about $70 billion in medical expenditures, lost productivity and other costs.

Signs of Depression

  • Inability to enjoy things that used to be pleasurable
  • Feelings of sadness or irritability
  • Loss of interest in work or leisure activities
  • Change in normal appetite or weight
  • Sleeping too much or too little
  • Fatigue or loss of energy
  • Difficulty concentrating or making decisions
  • Feelings of worthlessness, hopelessness, and helplessness
  • Increased pain or other stress related illness
  • Recurrent thoughts of death or suicide
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