Safety Signals in OCD

Organizations	Butler
Research Type	Clinical
Therapeutic Area of Study	Obsessive Compulsive Disorder (OCD)
Principal Investigators
Eligibility Criteria	If you are in between the ages of 18 and 65, in good overall health, and have been diagnosed with OCD (or are without any psychiatric diagnosis), you may be eligible to contribute to this study (see reverse side for contact information). We are looking for people who are willing to participate in both parts of the study. For those interested in the neuroimaging component of this study, please note that there are additional restrictions to participation in this study, including but not limited to the use of pacemakers and metal implants. Participation in this study involves a comprehensive interview about your mental health history; several paper-and-pencil and computer-based cognitive tests; a behavioral task involving a mild shock that will create a situation in which emotional learning may take place and allow the testing of your extinction recall capacity; and (optional) an MRI scan that will show us the parts of your brain used in emotional memory. Participation will take place over the course of two back-to-back days. The first will take about 4 hours, and the second will take about 1 hour. All information obtained from this study will remain strictly confidential. You will be compensated for your time.
Recruitment Status	Open
Date Study Started	01/01/2011
Date Study Ends	06/30/2013
Contact Information	For more information, please contact Alissa Cerny at (401) 455-6366
Description	The staff of the Translational OCD Program at Butler Hospital/Brown University are initiating a study on the processing of safety signals in participants with and without OCD. This study is conducted in two parts: one with and one without the use of magnetic resonance imaging (MRI). Using MRI, we can visualize the brain as you recall your emotional memories and further our knowledge on this unique disorder. Your participation in this study is invaluable to continued research into OCD.

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