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Butler Hospital
Butler Hospital

TOPS Study

What is the Purpose of the TOPS Study?

The aim of the TOPS (Tapering Off Pharmacotherapy Support) Study is to evaluate the discontinuation of long-term serotonin reuptake inhibitors (SRIs) in individuals with Obsessive Compulsive Disorder (OCD).  This study is funded by the National Institutes of Mental Health and conducted by researchers at Butler Hospital who are affiliated with the Alpert Medical School of Brown University.   


Individuals with OCD who wish to stop taking medication may be eligible if they are between the ages of 18-65 and have been taking an SRI for 2 years or more. 


Participation in TOPS involves an initial screening appointment to ensure eligibility that includes completion of interviews and questionnaires. Eligible individuals are then randomly assigned (by chance) to one of two 22-week programs using different techniques to help people come of medication.  

All study participants will receive:

  • a comprehensive assessment of their symptoms
  • one of two 22-week programs designed to support individuals coming off SRI medication
  • seven biweekly medication management sessions with an experienced study psychiatrist
  • compensation for time spent completing study assessments (up to $100 for full participation)

If you are interested in learning more about the TOPS study, please contact Dr. Boisseau at (401) 455-6236 or fill out the form below and a staff member can contact you.  Participation is voluntary. All information gathered will be treated as confidential.

(please specify am or pm)

TOPS Study FAQ's
  TOPS Study FAQ
Want to learn more about the TOPS Study for OCD? Visit our TOPS frequently asked questions page.
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