A 2018 award from the National Institute of General Medical Sciences (NIGMS) to Butler Hospital established the Center of Biomedical Research Excellence (COBRE) on Neuromodulation or CCN. The mission of Butler’s CCN is to support innovative clinical research in neuromodulation (brain stimulation) and the career development of investigators in this field. The work couples brain stimulation methods with readouts of brain activity (e.g., using various neuroimaging, behavioral, and physiological assessment methods) in clinical or clinically relevant populations. The CCN provides a platform for the exchange of scientific insights and technical skills and mentoring so project leaders can move towards scientific independence. A robust pilot project award program provides support for new proposals and scientists who stand to contribute to a sustainable pipeline of researchers in clinical neuromodulation. The CCN focuses on neuropsychiatric illness with the guiding principle that for noninvasive brain stimulation to gain clinical efficacy and implementation, it is imperative to better characterize clinically relevant target circuits and mechanisms of action.
The CCN includes (1) a Design and Analysis Core (DAC) to support rigorous and innovative experimental design and data analytic strategies; (2) a Neuromodulation and Neuroimaging Core (NNC) to facilitate the acquisition and processing of high-quality data using noninvasive neurostimulation and neuroimaging methods; (3) an Administrative Core to oversee and coordinate activities to propel the development of investigators towards independence. The CCN will identify and promote the success of new neuromodulation scientists through the recruitment of new PLs and through its Pilot Project program, integrating the resources of the DAC and NNC.
Our guiding scientific principle is that for the promise of neuromodulation therapies to be fully realized, it is critical to better characterizing their target circuits and mechanisms of action.
Our guiding organizational principle is to create structures and governance to propel promising junior investigators in this field towards independent scientific careers. This involves the following aims:
Implement our management plan and mentorship program to expand the group of clinical-translational researchers doing therapeutically relevant and mechanistically informative neuromodulation research in Rhode Island. We have developed research core resources for the RI scientific community. one to support research design and later data analysis and interpretation, and another to acquire neuromodulation and neuroimaging data using best practices. The administrative core oversees fiscal management, fosters CCN cohesion, and evaluates the Center’s overall progress.
The CCN Administrative Core, develops design/statistical, neuroimaging, and brain stimulation resources focusing particularly on COBRE projects and new pilot research. The CCN Administrative Core works closely with our partners. These include IDeA Networks of Biomedical Research Excellence (INBRE) Centers and IDeA-Clinical and Translational (CTR) programs in Rhode Island, collaborating entities at/affiliated with Brown University including the Brown Department of Psychiatry and Human Behavior (DPHB), Carney Institute for Brain Science, COBRE Center for Central Nervous System Function (CCNSF), Advance Clinical and Translational Research (Advance-CTR) and the Providence VA Medical Center for Neurorestoration and Neurotechnology (CfNN).
Director, COBRE Center for Neuromodulation
Dr. Benjamin Greenberg has a BA in psychology from Amherst College, a PhD in neurosciences from UC San Diego, and an MD from the University of Miami, with psychiatry residency at Johns Hopkins. He then led adult OCD research at NIMH, where he performed the first transcranial magnetic stimulation (TMS) study in that illness. At Butler Hospital and Brown since 2000, he has focused on invasive neurosurgeries including ventral capsulotomy and deep brain stimulation (DBS). FDA humanitarian approval of DBS for intractable OCD in 2009 was based on that work. His NIH funding has included R21, R01, U01, P50, and P20 grants. He has a secondary focus in psychiatric genetics. As a clinical psychiatrist, he has treated OCD for thirty years; and over the past five years has also treated PTSD, he previously led Butler outpatient services. He currently directs the COBRE Center for Neuromodulation at Butler Hospital and co-directs the Center for Neuromodulation and Neurotechnology (CfNN) at the Providence VAMC (PVAMC), in both roles focusing on noninvasive brain stimulation.
Deputy Director, COBRE CCN; Director, Neuromodulation & Neuroimaging Core
Linda L. Carpenter, MD is a Professor of Psychiatry in the Alpert Medical School of Brown University and Chief of the Mood Disorders Program at Butler Hospital. She completed her undergraduate psychology degree at the University of Michigan, her MD from the University of Pennsylvania. She did an internship in internal medicine, psychiatry residency training, and a clinical neuroscience research fellowship all at Yale University. She joined the Brown Psychiatry faculty at Brown in 1997 and has continued her path as a physician-scientist investigating the neurobiology of, and new treatments for, major depression and other mood and anxiety disorders at Butler Hospital. She led a 10-year, federally funded translational research program focusing on the development of laboratory biomarkers signaling risk for mood/anxiety disorders, and understanding the impact of early life stress on adult biology. She has also conducted a number of randomized clinical trials sponsored by industry and NIH, investigating investigational drugs and devices for treating depression, including esketamine, Vagus Nerve Stimulation (VNS), Deep Brain Stimulation (DBS), Transcranial Magnetic Stimulation (TMS), and transcranial Direct Current Stimulation (tDCS). She is the founding Director of the Butler Hospital TMS Clinic and Neuromodulation Research Facility. Her lab evaluates new neurostimulation treatments and their mechanisms, using both EEG and fMRI. In addition to her role as Deputy Director of the Butler COBRE Center, she is Director of the Neuromodulation and Neuroimaging Core. She works with the COBRE Project Leaders, Brown trainees, and other Brown-affiliated research faculty who incorporate noninvasive brain stimulation techniques into their clinical mechanisms and therapeutics research. Dr. Carpenter also chairs the Butler Hospital Institutional Review Board (IRB).
Dr. Tyrka received her MD and PhD in medicine and psychology through a combined program at the University of Pennsylvania. She completed a psychiatry residency at Brown Medical School and further research training in clinical neuroscience at the Mood Disorders Research Program and Laboratory for Clinical Neuroscience at Butler Hospital and Brown University. Dr. Tyrka is Professor of Psychiatry and Human Behavior at Brown. She is the Director of Research at Butler Hospital and Director of the Laboratory for Clinical and Translational Neuroscience. Director of Research Training and PI of the NIMH-funded R25 Research Training Program in the Brown psychiatry residency program, Dr. Tyrka is dedicated to mentoring and training. Dr. Tyrka's program of research is focused on discovering the social, behavioral and molecular mechanisms of risk and resilience in children and adults with a history of early adversity and trauma. She Co-Directs the Brown Psychiatry Initiative on Stress, Trauma, and Resilience, and a postdoctoral T32 research training program on this topic. Dr. Tyrka is Associate Director of the Administrative Core and leads the Mentorship Program of the Butler Hospital CCN.
Kristen Fortin-Ashburne obtained a BA in psychology (sociology minor) from the University of Massachusetts Dartmouth and MBA in Global Business Leadership (Organizational Leadership concentration) from Johnson & Wales University. She joined the CCN leadership team with over sixteen years’ experience in research, health care system administration, operations and project management. Prior to joining CCN, Ms. Fortin-Ashburne was Senior Clinical Research Technologist in Dr. Mary Carskadon’s E.P. Bradley Sleep Research Laboratory located on the Butler Hospital campus. Following her MBA, she was the clinical supervisor in the high-volume UMass Memorial Sleep Disorders Center. Later, she held the position of operations supervisor managing the overall business and academic operations of a large medical center in an underserved area, Tri River Family Health Center of the Blackstone Valley. In addition to CCN programmatic grant management, Ms. Fortin-Ashburne works closely with institutional senior leadership (notably our Hospital Advisory Committee) to streamline processes, enhance growth, and add efficiency to improve operations and quality of services.
The Hospital Advisory Committee (HAC) and Internal Advisory Committee (IAC) of the COBRE Center for Neuromodulation provide additional insight on COBRE development and implementation. The HAC members represent different areas of expertise relevant to Butler Hospital, Care New England hospital operations, and infrastructure design. The IAC members represent different areas of expertise relevant to partnering institutions and provide oversight on themes and operations, and are committed to the development of the Center. The primary role of the IAC has been to support the Executive Committee during COBRE implementation with four main advisory goals: 1) providing operational feedback based; 2) identifying cross-institutional resources and recommendations to enhance COBRE Cores, investigator projects, and mentorship program, and 3) guiding implementation and business plan toward a Phase II and Phase III.
Steven Burke, MBA, Vice President of Finance, Butler Hospital, Care New England
Mary Marran, MA, OT, MBA, Chair, President and Chief Operating Officer, Butler Hospital, Care New England
Steven Brown, ITILv3, IT Site Manager Academic and Research, Care New England
Guarav Choudhary, MD, Professor of Medicine, Associate Chief of Staff (Research), Providence VA Medical Center
John Davenport, PhD, Managing Director, Brown Institute of Brain Science, Brown University
Lawrence Price, MD, Professor of Psychiatry and Human Behavior, Brown University
Steve Rasmussen, MD, Professor of Psychiatry and Human Behavior; Chair of the Department of Psychiatry and Human Behavior at the Alpert Medical School Brown University
Sharon Rounds, MD, Associate Dean for Clinical Affairs, Professor of Medicine, Professor of Pathology and Laboratory Medicine, Director, Advance-CTR Brown University; Director of the CardioPulmonary Vascular Biology Center for Biomedical Research Excellence, Providence VA Medical Center
The External Advisory Committee (EAC) of the COBRE Center for Neuromodulation primary role is to participate in COBRE Center evaluation, including an evaluation of the Project Leaders’ progress, the effectiveness of the COBRE mentorship, and the usefulness of Core services. EAC members have been chosen for their robust backgrounds as leading investigators and mentors, their expertise in neuromodulation, and areas of expertise that are complementary to the COBRE projects.
Erika Forbes, PhD, Professor of Psychiatry, Pediatrics, Psychology and Clinical and Translational Science University of Pittsburgh
Mark George, MD, Endowed Chair, Layton McCurdy Endowed Chair in Psychiatry Medical University of South Carolina
Stephan Taylor, MD, EAC Chair, Professor and Associate Chair for Research and Research Regulatory Affairs University of Michigan
Eric Wassermann, MD, Investigator, Behavioral Neurology National Institute of Neurological Disorders and Stroke
Deputy Director, COBRE CCN; Director, Neuromodulation & Neuroimaging Core
Associate Director, Neuromodulation & Neuroimaging Core
Neuromodulation Research Facility Coordinator
Director, Design & Analysis Core
Co-Director, Design & Analysis Core
Associate Director, Design & Analysis Core
Project EPIC: Brain Circuitry of inhibitory control in young adults: Modulation with tDCS
Dr. McLaughlin is Assistant Professor of Psychiatry and Human Behavior at the Alpert Medical School of Brown University and a neuropsychologist at Butler Hospital. She completed a PhD in clinical psychology at Suffolk University and then postdoctoral training in neuropsychology at Brown University and Butler Hospital, where she directs its psychiatric neurosurgery program. She has extensively studied prefrontal-subcortical functioning across neuropsychiatric disorders, with a more recent emphasis on the assessment of brain changes after neurocircuit-based interventions. She continues this line of research as a CCN Project Leader in COBRE, with a project investigating the inhibitory control (IC) network in young adults with deficits in ‘real-world’ IC (implicated in many neuropsychiatric illnesses); and assesses how a noninvasive method, high-definition-transcranial direct current stimulation (HD-tDCS) modulates MRI measures of functional connectivity within that network.
Project RISE: Effects of tDCS timing on safety memory in PTSD
Dr. van’t Wout-Frank is Assistant Professor of Psychiatry and Human Behavior at Alpert Medical School, Brown University. She completed a doctoral degree in the Netherlands - where she was born - in cognitive neuropsychiatry, focusing on emotion processing in schizophrenia and related disorders. Following her PhD, Dr. van’t Wout-Frank continued work on emotional and social cognition at the University of Arizona, and later Brown University, in postdoctoral research on decision making. At Brown she became particularly interested in using noninvasive brain stimulation to understand and modify negative emotions, such as fear, regret and pain, and has worked to develop neuromodulation to treat posttraumatic stress disorder, in collaboration with the Center for Neurorestoration and Neurotechnology at the Providence VA Medical Center. Her CCN project extends that work by testing how the timing of noninvasive tDCS in a fear extinction paradigm affects safety learning, safety memory, and MRI-measured brain activity in individuals with posttraumatic stress symptoms, knowledge important to optimizing clinical neuromodulation.
Project FLEX: Modulating prefrontal circuits underlying behavioral flexibility in OCD: a TMS study
Sarah Garnaat, PhD, is Assistant Professor of Psychiatry and Human Behavior at the Alpert Medical School of Brown University and a Research Psychologist at Butler Hospital. A licensed clinical psychologist and clinical researcher, she completed her doctoral training at the University of Houston and a T32 postdoctoral fellowship in treatment research at Brown University. Dr. Garnaat is an investigator in the Brown & Butler OCD Research Group and has expertise in the assessment and treatment of obsessive-compulsive disorder (OCD) and anxiety disorders. Her current research efforts focus on use of neuroscientific approaches to better understand the brain in OCD and inform development of novel treatments for OCD and anxiety disorders, as well as use of noninvasive neuromodulation to enhance behavioral interventions. The goal of her project is to investigate brain networks underlying difficulty with behavioral flexibility in OCD, using transcranial magnetic stimulation (TMS) as a probe of the system and fMRI to measure functional changes within related brain networks.
Project TIPS: Determining whether TMS changes the brain through brain synaptic plasticity
Dr. Brown is an Assistant Professor (Research Scholar Track) in the Department of Psychiatry and Behavioral Health and a secondary appointment in Neurology at the Warren Alpert Medical School of Brown University. He is the Director of the Brown Brain Stimulation Laboratory (BBSL) and Associate Director of Transcranial Magnetic Stimulation (TMS) at Butler Hospital. He graduated from the University of Utah in Psychology (B.S.), and obtained his M.D. and Ph.D. from the Medical Scientist Training Program (MSTP) at the Medical College of Wisconsin studying mechanisms of synaptic plasticity. He completed a combined residency in both neurology and psychiatry, aka ‘brain medicine’, at the Medical University of South Carolina (MUSC) in 2020.
The Neuromodulation and Neuroimaging Core (NNC) facilitates the research goals of COBRE Project Leaders and pilot grant investigators and benefits the broader neuromodulation research community by providing expert support, training, assistance, and advice to its constituents in the practical aspects of implementation, data collection, and project management related to neuroimaging and neurostimulation methods. The NNC addresses a critical need, namely, to provide Project Leaders with unique resources, skills, and support for using the best methods and practices surrounding neuroimaging and neuromodulation in clinical neuropsychiatric populations. The NNC provides key services for research projects and creates an enduring resource that offers neuromodulation researchers a series of educational seminars, hands-on workshops, and customized training opportunities, high-level consultative and medical input, and use of a specialty research facility at Butler Hospital with lab space, equipment, and medical support.
The Design and Analysis Core (DAC) provides experimental design, statistical support, and neuroimaging consultation services to COBRE Project Leaders and the broader scientific research community. DAC faculty are affiliated with the Quantitative Sciences Program (QSP) of the Departments of Psychiatry and Neurology at the Alpert Medical School of Brown University and the Center for Neurorestoration and Neurotechnology at Providence VA Medical Center. Core Leader Richard Jones, ScD is a psychiatric epidemiologist and methodologies, and the director of the QSP. Core Co-Leader Jennifer Barredo, PhD is a neuroscientist with expertise in neuroimaging methodologies including advanced diffusion imaging, multimodal analysis, and machine learning. The DAC also maintains scientific computing resources and workflows available to COBRE project and pilot investigators and sponsors educational seminars and workshops.
Rich Jones, ScD
Jennifer Barredo, PhD
Quantitative Sciences Program of the Departments of Psychiatry and Neurology at the Alpert Medical School of Brown University and the Norman Prince Neurosciences Institute
The Monthly Brain Stimulation Meeting
The Monthly Brain Stimulation Meeting typically meets the last Friday of every month from 12:00 pm to 1:00 pm. This meeting brings together scientists, students, post-docs, graduate students, and research assistants from the research community to communicate the results of new research and topics relating to neuromodulation, neuroimaging, or electrophysiological studies of brain circuitry and dynamics relevant to neuromodulation.
To learn more about the Brain Stimulation meeting or if would like to request a guest speaker or research topic, please send inquiries to COBRECCN@CareNE.org (include your Name, institution, title, contact information).
The COBRE Center for Neuromodulation aims to increase the quantity and quality of research in clinical neuromodulation (brain stimulation) in Rhode Island. One means of attaining this goal is identifying and nurturing talented young neuromodulation investigators or established investigators who want to create a new research line in the arena of neuromodulation. The Pilot Program supports the COBRE’s growth by encouraging additional scholarship in the COBREs thematic areas and developing potential new COBRE Project Leaders.
Our Center will award up to three pilot project awards annually, depending on available funding, for research related to Neuromodulation. Neuromodulation research encompasses the development of new brain stimulation targets, therapeutic interventions, or the use of neuromodulatory tools to otherwise understand and address neuropsychiatric disorders or their mechanisms. We aim to enable investigators to collect preliminary data in support of grant applications for independent external research funding, especially from the NIH. Pilot project leaders can take advantage of the COBRE CCN community to help guide their science and career development.
Pilot project leaders will have access to the COBRE’s three interdisciplinary cores. These cores will provide infrastructure, consultation, and additional support services to ensure the successful career development of the funded junior investigator and help them apply for external, independent funding. The three Cores include an Administrative Core, a Design and Analysis Core (DAC), and a Neuromodulation and Neuroimaging Core (NNC).
RI-INBRE is pleased to host the Virtual North East Regional IDeA Conference v-NERIC 2021, August 16 – 18, 2021. The Northeast Regional Institutional Development Award (IDeA) Conference brings together individuals representing IDeA Networks of Biomedical Research Excellence (INBRE), Centers of Biomedical Research Excellence (COBRE), and IDeA Clinical and Translational Research programs from Delaware, Maine, New Hampshire, Rhode Island, and Vermont. This virtual event is offered at no charge!
New minimally invasive surgery for treatment-resistant obsessive-compulsive disorder. There's a new minimally invasive surgery for treatment-resistant obsessive-compulsive disorder. This condition, also known as OCD, affects some three million Americans each year. "OCD consists of obsessions which are intrusive, thoughts that are bothersome, that cause distress and then compulsions which people do in order to reduce the stress and anxiety," said Dr. Nicole McLaughlin, a neuropsychologist at Butler Hospital. by BARBARA MORSE, NBC 10 NEWS Read More
Dr. Linda Carpenter was named president-elect of the Society for Biological Psychiatry at the society’s annual meeting this month. Carpenter, professor of psychiatry and human behavior at Brown University and a member of the Carney Institute for Brain Science Executive Committee, was elected president of the society by peers in the field of biological psychiatry research. Read More
Meet a COBRE Center for Neuromodulation Project Leader
Joshua Brown, MD, PhD
Project: Determining whether TMS changes the brain through brain synaptic plasticity
Dr. Brown joined the COBRE Center for Neuromodulation in November 2020. Dr. Brown is an Assistant Professor (Research Scholar Track) in the Department of Psychiatry and Behavioral Health and a secondary appointment in Neurology at the Warren Alpert Medical School of Brown University. He is the Director of the Brown Brain Stimulation Laboratory (BBSL) and Associate Director of Transcranial Magnetic Stimulation (TMS) at Butler Hospital. He graduated from the University of Utah in Psychology (B.S.) and obtained his M.D. and Ph.D. from the Medical Scientist Training Program (MSTP) at the Medical College of Wisconsin studying mechanisms of synaptic plasticity. His CCN project proposes a series of experiments in healthy human subjects combining pharmacologic manipulation of the LTP and LTD cascades with TMS treatment protocols to the motor cortex. Electrophysiologic approaches assessing motor evoked potentials (MEPs) with electromyography (EMG) will allow further elucidation of the contribution of glutamatergic versus GABAergic inputs, and will directly impact stimulation strategies. A mechanistic understanding of TMS-induced changes to the brain could unleash its full therapeutic potential, and thereby, transform the treatment of brain disorders.
Research reported in this website was supported by the National Institute of General Medical Science of the National Institutes of Health under grant number P20GM130452. If you have received funding, consultation, mentorship, research support services, materials, training, access to shared equipment and/or space from the COBRE Center for Neuromodulation Cores, please acknowledge the COBRE Center for Neuromodulation by using the following statement:
Grant citing in all abstracts (presentations), and publications by investigators: “Research reported in this publication was supported by the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number P20GM130452, Center for Biomedical Research Excellence, Center for Neuromodulation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”
Core Facility users citing:
“Research was facilitated by the National Institute Of General Medical Sciences of the National Institutes of Health under Award Number P20GM130452, Center for Biomedical Research Excellence, Center for Neuromodulation. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health”
Please also send the title of your presentation, and where and when you presented the work or the citation for your manuscript. COBRECCN@CareNE.org
This portion of our website is supported by the COBRE Center of Neuromodulation Funded by the National Institutes of Health grant number P20GM130452. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health
Barredo J, Bozzay ML, Primack JM, Schatten HT, Armey MF, Carpenter LL, Philip NS. Translating Interventional Neuroscience to Suicide: It's About Time. Biol Psychiatry. 2021 Jun 1;89(11):1073-1083. doi: 10.1016/j.biopsych.2021.01.013. Epub 2021 Feb 1. PMID: 33820628.
Philip NS, Doherty RA, Faucher C, Aiken E, van 't Wout-Frank M. Transcranial Magnetic Stimulation for Posttraumatic Stress Disorder and Major Depression: Comparing Commonly Used Clinical Protocols. J Trauma Stress. 2021 May 11. doi: 10.1002/jts.22686. Epub ahead of print. PMID: 33973681.
Brigido S, Bozzay M, Philip NS. Posttraumatic Stress Disorder Symptom Severity Does Not Predict Depression Improvement, but May Impact Clinical Response and Remission. J Clin Psychiatry. 2021 Mar 30;82(3):20l13751. doi: 10.4088/JCP.20l13751. PMID: 34000108; PMCID: PMC8177072.
Cosmo C, Zandvakili A, Petrosino NJ, Berlow YA, Philip NS. Repetitive Transcranial Magnetic Stimulation for Treatment-Resistant Depression: Recent Critical Advances in Patient Care. Curr Treat Options Psychiatry. 2021 Mar 11:1-17. doi: 10.1007/s40501-021-00238-y. Epub ahead of print. PMID: 33723500; PMCID: PMC7946620.
Greenberg BD, Philip NS, Fortin-Ashburne K, Carpenter LL. The COBRE Center for Neuromodulation (CCN) at Butler Hospital: Clinical-Translational Research in Human Brain Stimulation. R I Med J (2013). 2021 Mar 1;104(2):30-33. PMID: 33648316.
Barredo J, Berlow Y, Swearingen HR, Greenberg BD, Carpenter LL, Philip NS. Multimodal Elements of Suicidality Reduction After Transcranial Magnetic Stimulation. Neuromodulation. 2021 Mar 1. doi: 10.1111/ner.13376. Epub ahead of print. PMID: 33650209.
Zandvakili A, Swearingen HR, Philip NS. Changes in functional connectivity after theta-burst transcranial magnetic stimulation for post-traumatic stress disorder: a machine-learning study. Eur Arch Psychiatry Clin Neurosci. 2021 Feb;271(1):29-37. doi: 10.1007/s00406-020-01172-5. Epub 2020 Jul 27. PMID: 32719969; PMCID: PMC7867551.
van 't Wout-Frank M, Philip NS. Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure J Vis Exp. 2021 Jan 18;(167):10.3791/61795. doi: 10.3791/61795. PMID: 33522512; PMCID: PMC8140328.
Berlow YA, Zandvakili A, Philip NS. Low-frequency right-sided and high frequency left-sided repetitive transcranial magnetic stimulation for depression: The evidence of equivalence. Brain Stimul. 2020 Nov-Dec;13(6):1793-1795. doi: 10.1016/j.brs.2020.10.005. Epub 2020 Oct 13. PMID: 33065359; PMCID: PMC7552991.
Kokdere F, Tirrell E, Fukuda AM, Gobin AP, Kavanaugh BC, Price LH, Carpenter LL. Do deviations from the 5 sessions per week schedule impact outcomes of transcranial magnetic stimulation for major depressive disorder? Brain Stimul. 2020 Nov-Dec;13(6):1491-1493. doi: 10.1016/j.brs.2020.08.001. Epub 2020 Aug 6. PMID: 32768691; PMCID: PMC8111778.
Fukuda AM, Hindley LE, Kang JWD, Tirrell E, Tyrka AR, Ayala A, Carpenter LL. Peripheral vascular endothelial growth factor changes after transcranial magnetic stimulation in treatment-resistant depression. Neuroreport. 2020 Nov 4;31(16):1121-1127. doi: 10.1097/WNR.0000000000001523. PMID: 32956213; PMCID: PMC7541741.
van 't Wout-Frank M, Shea MT, Sorensen DO, Faucher CR, Greenberg BD, Philip NS. A Secondary Analysis on Effects of Theta Burst Transcranial Magnetic Stimulation to Reduce Anger in Veterans With Posttraumatic Stress Disorder. Neuromodulation. 2020 Sep 17. doi: 10.1111/ner.13256. Epub ahead of print. PMID: 32945055.
Silveira VP, Frydman I, Fontenelle LF, Mattos P, de Oliveira-Souza R, Moll J, Hoexter MQ, Miguel EC, McLaughlin NCR, Shephard E, Batistuzzo MC. Exploring response inhibition and error monitoring in obsessive-compulsive disorder. J Psychiatr Res. 2020 Jul;126:26-33. doi: 10.1016/j.jpsychires.2020.04.002. Epub 2020 Apr 21. PMID: 32413597; PMCID: PMC7313630.
Bozzay ML, Primack J, Barredo J, Philip NS. Transcranial magnetic stimulation to reduce suicidality - A review and naturalistic outcomes. J Psychiatr Res. 2020 Jun;125:106-112. doi: 10.1016/j.jpsychires.2020.03.016. Epub 2020 Mar 28. PMID: 32251917; PMCID: PMC7197489.
Philip NS, McLaughlin NC, Carpenter LL, Phillips ML, Liu H, Haber SN, Greenberg BD. Transient aphasia induced by intermittent theta-burst stimulation. Brain Stimul. 2020 Jul-Aug;13(4):941-942. doi: 10.1016/j.brs.2020.03.013. Epub 2020 Mar 25. PMID: 32380444; PMCID: PMC7343258.
Petrosino NJ, Wout-Frank MV', Aiken E, Swearingen HR, Barredo J, Zandvakili A, Philip NS. One-year clinical outcomes following theta-burst stimulation for post-traumatic stress disorder. Neuropsychopharmacology. 2020 May;45(6):940-946. doi: 10.1038/s41386-019-0584-4. Epub 2019 Dec 3. PMID: 31794974; PMCID: PMC7162862.
Beck QM, Tirrell E, Fukuda AM, Kokdere F, Carpenter LL. Can early treatment response serve as a predictor of antidepressant outcome of repetitive Transcranial Magnetic Stimulation? Brain Stimul.2020 Mar-Apr;13(2):420-421. doi: 10.1016/j.brs.2019.12.002. Epub 2019 Dec 16. PMID: 31882372; PMCID: PMC8094132.
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