Research at Butler Hospital

We want to compare two treatments for depression: a gentle, easy-to-do form and a talk therapy called behavior activation.

The purpose of this research is to evaluate whether a take-home, self-administered, neurostimulation device called Relivion®DP is safe and helpful for reducing symptoms of Major Depressive Disorder (MDD). 

The purpose of this study is to look at how thoughts and emotions change during depression treatment. 

 

The purpose of this study is to understand whether esketamine effectively treats treatment-resistant depression (TRD) as a monotherapy. 

A Phase III, double-blinded, placebo-controlled study with a treatment arm. Eligible participants will be randomly assigned to receive either the investigational medication, BAN2401, or placebo.

This is an observational study to learn more about assessing potential risk for developing Alzheimer’s disease (AD) using biomarker research.

 

 

A longitudinal, observational study for individuals in ADAD families. ADAD is a genetic mutation that typically causes memory loss and dementia in the 30s to 50s.

The purpose of the Janssen AuTonomy trial is to assess the ability of the investigational medication in slowing the cognitive decline in participants with Early AD, as well as its safety and tolerability.

An observational study exploring the development of early-onset Alzheimer’s disease and how it compares to the more common late-onset Alzheimer’s disease.

The purpose of this study is to look at the safety and tolerability of Emtricitabine (FTC, Emtriva©, Gilead) in treating participants with MCI or mild to moderate AD.

A study for individuals in early recovery from opioid use and taking the medication buprenorphine (suboxone). Participants will engage in 5 sessions of active or placebo transcranial direct stimulation (tDCS) during the course of this 2-week study.

The goal of Project Start is to develop and evaluate different interventions aimed at increasing Disulfiram (Antabuse) medication adherence.

The Yoga MAT Study is testing a yoga intervention that involves 12 weeks of online yoga classes for people with chronic pain who are prescribed methadone or buprenorphine (Suboxone). 

The purpose of this study is to better understand how the brain works to allow people with OCD to make decisions and accomplish goals.

We are looking for healthy individuals with no psychiatric diagnoses to help us study how the brain works as it makes decisions to accomplish a goal. 

Project PROVOC is a research study investigating differences in brain circuitry between people with OCD and those with either a specific phobia or no history of psychiatric diagnosis.

Project FLEX is a research study examining how the brain shifts back and forth between different demands, which may help researchers develop new treatment options for OCD. To do this, participants with and without OCD will be asked to engage in questionnaires, functional magnetic resonance imaging (fMRI) scans, and transcranial magnetic stimulation (TMS), a form of noninvasive brain stimulation.

Project FLEX is a research study examining how the brain shifts back and forth between different demands, which may help researchers develop new treatment options for OCD. To do this, participants with and without OCD will be asked to engage in questionnaires, functional magnetic resonance imaging (fMRI) scans, and transcranial magnetic stimulation (TMS), a form of noninvasive brain stimulation.

Project STIM is a research study testing how TMS may change brain activity and symptoms in people with OCD.

Project STIM is seeking healthy individuals (without any medical or psychiatric disorders) to participate as “healthy comparisons” in our Project STIM study group. 

The Core Features study will utilize interviews, self-report questionnaires, computerized tasks, and magnetic resonance imaging (MRI), to better explain certain concepts as they relate to OCD and anxiety disorders.

A study examining factors that may have influenced a decision whether or not to be vaccinated against COVID-19 while pregnant.

Determining whether TMS changes the brain through synaptic plasticity.

Project EPIC is a research study that is investigating the brain regions responsible for inhibitory control, and whether these regions can be changed using non-invasive brain stimulation.

Research Investigating Stimulation for Extinction in PTSD.

We are looking for healthy volunteers with no psychiatric diagnoses to help us compare to those with Major Depressive Disorder.