--- title: Dominantly Inherited Alzheimer's Network (DIAN) description: DIAN is an international research partnership of leading scientists determined to understand a rare, early onset form of Alzheimer’s disease caused by a genetic mutation in one of three genes. image: https://www.butler.org/hubfs/-%20BUTLER/ButlerHospitalResearchStudy.jpg --- - [**Pay My Bill](https://www.carenewengland.org/pay/butler-hospital/) - [**Careers](https://www.butler.org/careers) - [**Donate](https://www.butler.org/ways-to-give) - [**My Chart](https://www.carenewengland.org/mychart) - [**+1 (844) 401-0111](tel:+1%20(844)%20401-0111) [![CNE Butler Behavioral Health](https://www.butler.org/hs-fs/hubfs/-%20CNE/CNE%20-%202026%20Branding/CNE%20Butler%20Behavioral%20Health.png?width=1200&height=475&name=CNE%20Butler%20Behavioral%20Health.png)](https://www.butler.org/) ** #### Site Search ** ** ![ # Dominantly Inherited Alzheimer's Network (DIAN) #### What is the DIAN Study? This is a longitudinal, observational study for individuals in ADAD families. Participants will visit Butler Hospital every other year for memory testing, brain scans, and laboratory procedures. During intervening years, a research coordinator will conduct an assessment over the phone #### What is the Purpose of the DIAN Study? DIAN is an international research partnership of leading scientists determined to understand a rare, early onset form of Alzheimer’s disease caused by a genetic mutation in one of three genes. Autosomal Dominant Alzheimer’s disease (ADAD) typically causes memory loss and dementia in the 30’s to 50’s and has a strong family history with approximately 50 percent of descendants being affected by the disease. ADAD is very rare as it makes up only 1 percent of the total cases of Alzheimer’s disease. Understanding this form of early, familial Alzheimer's disease may provide clues to decoding other dementias and may aide in developing dementia treatments. #### Eligibility DIAN is currently enrolling study participants who are biological adult children of a parent who carries a genetic mutation known to cause a rare, early onset form of Alzheimer’s disease. Study participants must be younger than the age at which their parent began displaying Alzheimer’s symptoms. Participants may or may not carry the gene themselves and may or may not have disease symptoms. Interested individuals can learn more about their eligibility by contacting the Memory and Aging Program Outreach Team at 401-455-6402 or by sending an email to [memory@butler.org](mailto:memory@butler.org).   To learn more about the Dominantly Inherited Alzheimer’s Network, its research, the families involved and the latest news visit [dian.wustl.edu](https://dian.wustl.edu/). #### Contact Form If you are interested in learning more about this study, please fill out the form below.  [Click here to subscribe to our monthly Memory Matters e-newsletter >>](https://www.butler.org/map-newsletter) **Organization** Butler Hospital **Area of Study** Memory and Aging **Status** Active ##### Contact Us [Send Us A Message](https://www.butler.org/contact-us) [+1 (844) 401-0111](tel:+18444010111) 345 Blackstone Blvd, Providence, RI 02906 - [**](https://www.facebook.com/ButlerHospital) - [**](https://twitter.com/ButlerHospital) - [**](https://www.linkedin.com/company/butler-hospital/) ##### Other Care New England Locations [Care New England](https://www.carenewengland.org/) [Kent Hospital](https://www.kentri.org/) [The Providence Center](https://providencecenter.org/) [VNA of Care New England](https://www.vnacarenewengland.org/) [Women & Infants Hospital](https://www.womenandinfants.org/) ##### Patients and Visitors [Find A Provider](https://www.butler.org/provider-finder) [Integra Community Care](https://www.integracare.org/) ##### About Us [Who We Are](https://www.butler.org/about) [Diversity, Equity, & Inclusion (DEI)](https://www.carenewengland.org/dei) [Research](https://www.butler.org/research) [Legal Notices](https://www.carenewengland.org/legal-notices) [Auxiliary Aids & Services](https://www.carenewengland.org/auxiliary-aids-and-services) [Price Transparency](https://www.carenewengland.org/price-transparency) ##### Get Involved [Ways to Give](https://www.butler.org/ways-to-give) [Careers](https://www.carenewengland.org/careers) [Volunteer](https://www.carenewengland.org/volunteer) ##### News [In The News](https://www.butler.org/news) [Media Relations](https://www.butler.org/media-relations) --- Copyright © 2026 Care New England Health System × You are about to leave our website and enter an external site. We are not responsible for the content, privacy practices, or accuracy of information on the external site. Do you wish to continue? [Yes](https://www.butler.org/studies/dominantly-inherited-alzheimers-network-dian#yes)   [No](https://www.butler.org/studies/dominantly-inherited-alzheimers-network-dian#no)